購物車
幫助
021-54845833/15800441009
中文名稱： 兔抗ABCC2多克隆抗體
英文名稱： Anti-ABCC2 rabbit polyclonal antibody
別 名： DJS; MRP2; cMRP; ABC30; CMOAT
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
反應(yīng)種屬： Human
相關(guān)類別： 一抗
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
|
Background: |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. |
|
Applications: |
ELISA, IHC |
|
Name of antibody: |
ABCC2 |
|
Immunogen: |
Synthetic peptide of humanABCC2 |
|
Full name: |
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
|
Synonyms： |
DJS; MRP2; cMRP; ABC30; CMOAT |
|
SwissProt: |
Q92887 |
|
ELISA Recommended dilution: |
2000-10000 |
|
IHC positive control: |
Human liver cancer |
|
IHC Recommend dilution: |
30-150 |
