購物車
幫助
021-54845833/15800441009
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Background: |
The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance. |
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Applications: |
WB, IHC |
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Name of antibody: |
ROR2 |
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Immunogen: |
Fusion protein of human ROR2 |
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Full name: |
receptor tyrosine kinase like orphan receptor 2 |
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Synonyms: |
BDB; BDB1; NTRKR2 |
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SwissProt: |
Q01974 |
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IHC positive control: |
Human prostate cancer and Human ovarian cancer |
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IHC Recommend dilution: |
200-500 |
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WB Predicted band size: |
105 KD |
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WB Positive control: |
Hela, K562, HepG2 and SH-SY5Y cell lysates |
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WB Recommended dilution: |
200-1000 |
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