購物車
幫助
021-54845833/15800441009
技術(shù)規(guī)格
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Background: |
This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. |
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Applications: |
WB |
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Name of antibody: |
PRMT1 |
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Immunogen: |
Fusion protein of human PRMT1 |
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Full name: |
protein arginine methyltransferase 1 |
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Synonyms: |
ANM1; HCP1; IR1B4; HRMT1L2 |
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SwissProt: |
Q99873 |
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WB Predicted band size: |
42 kDa |
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WB Positive control: |
SW480, Hela and A549 cell lysates |
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WB Recommended dilution: |
1000-5000 |
