購物車
幫助
021-54845833/15800441009
中文名稱：ADAM15 抗原（重組蛋白）
英文名稱： ADAM15 Antigen (Recombinant Protein)
別 名： ADAM metallopeptidase domain 15; MDC15
儲 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 213-414 amino acids of human ADAM15 |
|
Full name: |
ADAM metallopeptidase domain 15 |
|
Synonyms: |
MDC15 |
|
Swissprot: |
Q13444 |
|
Gene Accession: |
BC014566 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. |
