購物車
幫助
021-54845833/15800441009
|
Full name: |
coagulation factor VII (serum prothrombin conversion accelerator) |
|
Synonyms: |
SPCA |
|
Swissprot: |
P08709 |
|
Gene Accession: |
BC130468 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
- 首頁
- 科研產(chǎn)品
ELISA試劑盒
PCR試劑盒
生化試劑盒
細胞系
細胞庫
基礎(chǔ)培養(yǎng)基
完全培養(yǎng)基
原代細胞
細胞專用培養(yǎng)基
菌株
生化試劑
病理染色液
科研抗體
標(biāo)準(zhǔn)品
血清
- 公司簡介
- 公司新聞
- 技術(shù)服務(wù)
- 代理品牌
- 訂購中心
- 加入通蔚
