購物車
幫助
021-54845833/15800441009
|
Full name: |
MHC class I polypeptide-related sequence A |
|
Synonyms: |
MIC-A; PERB11.1 |
|
Swissprot: |
Q29983 |
|
Gene Accession: |
BC016929 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. |
- 首頁
- 科研產(chǎn)品
ELISA試劑盒
PCR試劑盒
生化試劑盒
細(xì)胞系
細(xì)胞庫
基礎(chǔ)培養(yǎng)基
完全培養(yǎng)基
原代細(xì)胞
細(xì)胞專用培養(yǎng)基
菌株
生化試劑
病理染色液
科研抗體
標(biāo)準(zhǔn)品
血清
- 公司簡介
- 公司新聞
- 技術(shù)服務(wù)
- 代理品牌
- 訂購中心
- 加入通蔚
