購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： EDA2R抗原（重組蛋白）
英文名稱： EDA2R Antigen (Recombinant Protein)
別 名： XEDAR; EDAA2R; EDA-A2R; TNFRSF27
儲(chǔ) 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概 述：
|
Fusion protein corresponding to a region derived from C terminal 138 amino acids of human EDA2R |
|
Full name: |
ectodysplasin A2 receptor |
|
Synonyms: |
XEDAR; EDAA2R; EDA-A2R; TNFRSF27 |
|
Swissprot: |
Q9HAV5 |
|
Gene Accession: |
BC034919 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Alternatively spliced transcript variants have been found for this gene. |
