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中文名稱：兔抗DDIT4L多克隆抗體

英文名稱： Anti-DDIT4L rabbit polyclonal antibody

別名： REDD2; Rtp801L

相關類別：一抗

抗原： DDIT4L

儲存： 冷凍（-20℃）

宿主： Rabbit

反應種屬： Human, Mouse, Rat

標記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

REDD-2 (regulated in development and DNA damage response 2), also designated Rtp801L or DDIT4L (DNA-damage-inducible transcript 4-like), is a 193 amino acid cytoplasmic protein belonging to the DDIT4 family and is predominantly expressed in skeletal muscle. Considered a stress-inducted protein, REDD-2 is a negative regulator of the mTOR (mammalian target of rapamycin) pathway. mTOR is a serine/threonine kinase that plays an essential role in cell growth control and is an important regulator of skeletal muscle size. Highly expressed in human atherosclerotic lesions and macrophages, REDD-2 mediates monocyte cell death through reduction of Trx (thioredoxin-1) expression. REDD2 expression in macrophages increases oxidized LDL (oxLDL)-induced cell death, suggesting that REDD2 may play a critical role in arterial pathology.

Applications:

ELISA, IHC

Name of antibody:

DDIT4L

Immunogen:

Fusion protein of human DDIT4L

Full name:

DNA-damage-inducible transcript 4-like

Synonyms：

REDD2; Rtp801L

SwissProt:

Q96D03

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

25-100

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細胞系

細胞庫

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完全培養(yǎng)基

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細胞專用培養(yǎng)基

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兔抗DDIT4L多克隆抗體

Background:	REDD-2 (regulated in development and DNA damage response 2), also designated Rtp801L or DDIT4L (DNA-damage-inducible transcript 4-like), is a 193 amino acid cytoplasmic protein belonging to the DDIT4 family and is predominantly expressed in skeletal muscle. Considered a stress-inducted protein, REDD-2 is a negative regulator of the mTOR (mammalian target of rapamycin) pathway. mTOR is a serine/threonine kinase that plays an essential role in cell growth control and is an important regulator of skeletal muscle size. Highly expressed in human atherosclerotic lesions and macrophages, REDD-2 mediates monocyte cell death through reduction of Trx (thioredoxin-1) expression. REDD2 expression in macrophages increases oxidized LDL (oxLDL)-induced cell death, suggesting that REDD2 may play a critical role in arterial pathology.
Applications:	ELISA, IHC
Name of antibody:	DDIT4L
Immunogen:	Fusion protein of human DDIT4L
Full name:	DNA-damage-inducible transcript 4-like
Synonyms：	REDD2; Rtp801L
SwissProt:	Q96D03
ELISA Recommended dilution:	1000-2000
IHC positive control:	Human thyroid cancer
IHC Recommend dilution:	25-100