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中文名稱：兔抗DROSHA多克隆抗體

英文名稱： Anti-DROSHA rabbit polyclonal antibody

別名： RN3; ETOHI2; RNASEN; RANSE3L; RNASE3L; HSA242976

抗原： DROSHA

相關(guān)類別： 一抗

儲(chǔ) 存： 冷凍（-20℃）

宿主： Rabbit

反應(yīng)種屬： Human, Mouse

標(biāo) 記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer.

Applications:

ELISA, IHC

Name of antibody:

DROSHA

Immunogen:

Synthetic peptide of human DROSHA

Full name:

drosha ribonuclease III

Synonyms:

RN3; ETOHI2; RNASEN; RANSE3L; RNASE3L; HSA242976

SwissProt:

Q9NRR4

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer;

IHC Recommend dilution:

30-150

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兔抗DROSHA多克隆抗體說明書
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細(xì)胞系

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原代細(xì)胞

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菌株

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病理染色液

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兔抗DROSHA多克隆抗體

Background:	This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer.
Applications:	ELISA, IHC
Name of antibody:	DROSHA
Immunogen:	Synthetic peptide of human DROSHA
Full name:	drosha ribonuclease III
Synonyms:	RN3; ETOHI2; RNASEN; RANSE3L; RNASE3L; HSA242976
SwissProt:	Q9NRR4
ELISA Recommended dilution:	5000-10000
IHC positive control:	Human esophagus cancer;
IHC Recommend dilution:	30-150