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  • RPSA抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW19781
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:60
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中文名稱: RPSA抗原(重組蛋白)

英文名稱: RPSA Antigen (Recombinant Protein)

別     名:  SA; LBP; LRP; p40; 67LR; lamR; 37LRP; LAMBR; LAMR1;
LRP/LR; LBP/p40; NEM/1CHD4

儲     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概     述

Full length fusion protein

技術(shù)規(guī)格

Full name:

ribosomal protein SA

Synonyms:

SA; LBP; LRP; p40; 67LR; lamR; 37LRP; LAMBR; LAMR1; LRP/LR; LBP/p40; NEM/1CHD4

Swissprot:

P08865

Gene Accession:

BC013827

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene



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