購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱： 兔抗UBXN1多克隆抗體
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Background: |
Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
UBXN1 |
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Immunogen: |
Full length fusion protein |
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Full name: |
UBX domain protein 1 |
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Synonyms: |
2B28; SAKS1; UBXD10 |
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SwissProt: |
Q04323 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human thyroid cancer and Human cervical cancer |
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IHC Recommend dilution: |
40-200 |
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WB Predicted band size: |
33 kDa |
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WB Positive control: |
Mouse brain tissue，Hela and HEPG2 cell lysates |
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WB Recommended dilution: |
500-2000 |
