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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW20493
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:80
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中文名稱: 兔抗NARF多克隆抗體


英文名稱: Anti-NARF rabbit polyclonal antibody


別       名: nuclear prelamin A recognition factor; IOP2


相關(guān)類別: 一抗


儲(chǔ)       存: 冷凍(-20℃)


宿       主: Rabbit


抗       原: NARF


反應(yīng)種屬: Human, Mouse, Rat


標(biāo)  記  物: Unconjugate


克隆類型: rabbit polyclonal


技術(shù)規(guī)格

Background:

Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. The protein encoded by this gene binds to the prenylated prelamin A carboxyl-terminal tail domain. It may be a component of a prelamin A endoprotease complex. The encoded protein is located in the nucleus, where it partially colocalizes with the nuclear lamina. It shares limited sequence similarity with iron-only bacterial hydrogenases. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene, including one with a novel exon that is generated by RNA editing.

Applications:

ELISA, IHC

Name of antibody:

NARF

Immunogen:

Fusion protein of human NARF

Full name:

nuclear prelamin A recognition factor

Synonyms:

IOP2

SwissProt:

Q9UHQ1

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human ovarian cancer

IHC Recommend dilution:

50-300




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