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中文名稱(chēng)：兔抗RUNX1(Ab-435) 多克隆抗體
英文名稱(chēng)： Anti-RUNX1(Ab-435) rabbit polyclonal antibody
別 名： AML1; CBFA2; EVI-1; AMLCR1; PEBP2aB; AML1-EVI-1
相關(guān)類(lèi)別： 一抗
儲(chǔ) 存： 冷凍（-20℃） 避光
抗 原： RUNX1(Ab-435)
宿 主： Rabbit
反應(yīng)種屬： Human
標(biāo)記物： Unconjugate
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits KAT6B-dependent transcriptional activation. |
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Applications: |
WB |
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Name of antibody: |
RUNX1(Ab-435) |
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Immunogen: |
Synthesized non-phosphopeptide derived from human AML1 around the phosphorylation site of serine 435 (S-N-S(p)-P-T). |
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Full name: |
runt-related transcription factor 1 |
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Synonyms： |
AML1; CBFA2; EVI-1; AMLCR1; PEBP2aB; AML1-EVI-1 |
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SwissProt: |
Q01196 |
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WB Predicted band size: |
49 kDa |
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WB Positive control: |
HepG2 cells treated with PMA (125ng/ml, 30mins) lysate |
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WB Recommended dilution: |
500-3000 |
