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中文名稱： 兔抗PRKAR2B(Ab-113) 多克隆抗體
英文名稱： Anti-PRKAR2B(Ab-113) rabbit polyclonal antibody
別 名： PRKAR2; RII-BETA
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃） 避光
抗 原： PRKAR2B(Ab-113)
宿 主： Rabbit
反應(yīng)種屬： Human Mouse Rat
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. |
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Applications: |
WB, IHC |
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Name of antibody: |
PRKAR2B(Ab-113) |
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Immunogen: |
Synthesized non-phosphopeptide derived from human PKA-R2β around the phosphorylation site of serine 113 (R-A-S(p)-V-C). |
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Full name: |
protein kinase, cAMP-dependent, regulatory, type II, beta |
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Synonyms： |
PRKAR2; RII-BETA |
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SwissProt: |
P31323 |
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IHC positive control: |
Human colon carcinoma tissue |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
46 kDa |
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WB Positive control: |
HepG2 cells and K562 cells lysates |
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WB Recommended dilution: |
500-3000 |
