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中文名稱：兔抗TNFSF11多克隆抗體

英文名稱： Anti-TNFSF11 rabbit polyclonal antibody

別名： ODF; OPGL; sOdf; CD254; OPTB2; RANKL; TNLG6B; TRANCE; hRANKL2

相關(guān)類別：一抗

抗原： TNFSF11

儲(chǔ) 存： 冷凍（-20℃）

宿主： Rabbit

反應(yīng)種屬： Human, Mouse, Rat

標(biāo) 記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been found.

Applications:

ELISA, IHC

Name of antibody:

TNFSF11

Immunogen:

Synthetic peptide corresponding to a region derived from 304-317 amino acids of human TNFSF11

Full name:

tumor necrosis factor superfamily member 11

Synonyms:

ODF; OPGL; sOdf; CD254; OPTB2; RANKL; TNLG6B; TRANCE; hRANKL2

SwissProt:

O14788

ELISA Recommended dilution:

5000-10000

IHC Positive control:

Human esophagus cancer;Human brain

IHC Recommended dilution:

20-100

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兔抗TNFSF11多克隆抗體說(shuō)明書(shū)
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021-54845833/15800441009

ELISA試劑盒

PCR試劑盒

生化試劑盒

細(xì)胞系

細(xì)胞庫(kù)

基礎(chǔ)培養(yǎng)基

完全培養(yǎng)基

原代細(xì)胞

細(xì)胞專用培養(yǎng)基

菌株

生化試劑

病理染色液

科研抗體

標(biāo)準(zhǔn)品

血清

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兔抗TNFSF11多克隆抗體

Background:	This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been found.
Applications:	ELISA, IHC
Name of antibody:	TNFSF11
Immunogen:	Synthetic peptide corresponding to a region derived from 304-317 amino acids of human TNFSF11
Full name:	tumor necrosis factor superfamily member 11
Synonyms:	ODF; OPGL; sOdf; CD254; OPTB2; RANKL; TNLG6B; TRANCE; hRANKL2
SwissProt:	O14788
ELISA Recommended dilution:	5000-10000
IHC Positive control:	Human esophagus cancer;Human brain
IHC Recommended dilution:	20-100