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中文名稱 : 小鼠抗ATG4B單克隆抗體

英文名稱： Anti-ATG4B mouse monoclonal antibody

別名： autophagy related 4B cysteine peptidase; APG4B; AUTL1

相關(guān)類別：一抗

儲存： 冷凍（-20℃）

宿主： Mouse

抗原： ATG4B

反應(yīng)種屬： Human

標(biāo) 記物： Unconjugate

克隆類型： mouse monoclonal

技術(shù)規(guī)格

Background:

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Applications:

WB, IHC

Name of antibody:

ATG4B

Immunogen:

Fusion protein of human ATG4B

Full name:

autophagy related 4B cysteine peptidase

Synonyms:

APG4B; AUTL1

SwissProt:

Q9Y4P1

IHC positive control:

Human endometrial cancer

IHC Recommend dilution:

500-2000

WB Predicted band size:

44 KD

WB Positive control:

Ramos, 293T, Jurkat, Hela, COLO205, U251, PC3 cell lysates

WB Recommended dilution:

500-2000

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小鼠抗ATG4B單克隆抗體

Background:	Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Applications:	WB, IHC
Name of antibody:	ATG4B
Immunogen:	Fusion protein of human ATG4B
Full name:	autophagy related 4B cysteine peptidase
Synonyms:	APG4B; AUTL1
SwissProt:	Q9Y4P1
IHC positive control:	Human endometrial cancer
IHC Recommend dilution:	500-2000
WB Predicted band size:	44 KD
WB Positive control:	Ramos, 293T, Jurkat, Hela, COLO205, U251, PC3 cell lysates
WB Recommended dilution:	500-2000