購物車
幫助
021-54845833/15800441009
中文名稱：TLE6 抗原（重組蛋白）
英文名稱： TLE6 Antigen (Recombinant Protein)
別 名： transducin like enhancer of split 6; GRG6; PREMBL
儲 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 373-572 amino acids of human TLE6 |
|
Full name: |
transducin like enhancer of split 6 |
|
Synonyms: |
GRG6; PREMBL |
|
Swissprot: |
Q9H808 |
|
Gene Accession: |
BC020206 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a member of the Groucho/ transducin-like Enhancer of split family of transcriptional co-repressors. The encoded protein is a component of the mammalian subcortical maternal complex, which is required for preimplantation development. In mouse, knock out of this gene results in cleavage-stage embryonic arrest resulting from defective cytoplasmic F-actin meshwork formation and asymmetric cell division. In human, an allelic variant in this gene is associated with preimplantation embryonic lethality. Alternative splicing results in multiple transcript variants. |
