購(gòu)物車
幫助
021-54845833/15800441009
宿 主： Rabbit
抗 原： HDAC3
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
技術(shù)規(guī)格
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Background: |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. |
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Applications: |
ELISA, WB |
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Name of antibody: |
HDAC3 |
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Immunogen: |
Synthetic peptide of human HDAC3 |
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Full name: |
histone deacetylase 3 |
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Synonyms： |
HD3; RPD3; RPD3-2 |
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SwissProt: |
O15379 |
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ELISA Recommended dilution: |
1000-2000 |
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WB Predicted band size: |
49 kDa |
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WB Positive control: |
A549, NIH/3T3, Raji, 293T and Hela cells |
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WB Recommended dilution: |
200-1000 |
